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Muzafar A Macha Selected Research

pregna-4,17-diene-3,16-dione (guggulsterone)

12/2013Guggulsterone decreases proliferation and metastatic behavior of pancreatic cancer cells by modulating JAK/STAT and Src/FAK signaling.
3/2011Guggulsterone (GS) inhibits smokeless tobacco and nicotine-induced NF-κB and STAT3 pathways in head and neck cancer cells.
2/2011Guggulsterone targets smokeless tobacco induced PI3K/Akt pathway in head and neck cancer cells.
11/201014-3-3 zeta is a molecular target in guggulsterone induced apoptosis in head and neck cancer cells.

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Muzafar A Macha Research Topics

Disease

36Neoplasms (Cancer)
11/2022 - 05/2009
14Squamous Cell Carcinoma of Head and Neck
12/2021 - 05/2009
9Neoplasm Metastasis (Metastasis)
01/2022 - 03/2011
7Carcinogenesis
12/2021 - 05/2009
7Pancreatic Neoplasms (Pancreatic Cancer)
04/2019 - 10/2012
4Glioblastoma (Glioblastoma Multiforme)
10/2021 - 04/2018
3Inflammation (Inflammations)
01/2022 - 03/2015
3Head and Neck Neoplasms (Head and Neck Cancer)
03/2011 - 11/2010
2Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 05/2016
2Leukoplakia
10/2021 - 07/2010
2Adenocarcinoma
02/2016 - 10/2012
2Mouth Neoplasms (Oral Cancer)
07/2010 - 05/2009
1Triple Negative Breast Neoplasms
11/2022
1Circulating Neoplastic Cells
01/2022
1Esophageal Neoplasms (Esophageal Cancer)
01/2021
1Adenocarcinoma of Lung
01/2021
1Parkinson Disease (Parkinson's Disease)
01/2021
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2021
1Adenoma (Adenomas)
05/2016
1Acquired Immunodeficiency Syndrome (AIDS)
11/2015
1Lymphatic Metastasis
04/2015
1Lung Neoplasms (Lung Cancer)
01/2015
1Basal Cell Carcinoma (Rodent Ulcer)
01/2013
1Disease Progression
05/2009
1Hyperplasia
05/2009

Drug/Important Bio-Agent (IBA)

8Proteins (Proteins, Gene)FDA Link
04/2021 - 05/2009
6MucinsIBA
08/2018 - 10/2012
4ChemokinesIBA
11/2022 - 01/2021
4MicroRNAs (MicroRNA)IBA
01/2022 - 01/2014
4Biomarkers (Surrogate Marker)IBA
12/2020 - 01/2014
4pregna-4,17-diene-3,16-dione (guggulsterone)IBA
12/2013 - 11/2010
3CytokinesIBA
01/2022 - 01/2021
3Temozolomide (Temodar)FDA LinkGeneric
10/2021 - 06/2019
3AfatinibIBA
10/2021 - 03/2017
3Biological ProductsIBA
11/2020 - 03/2011
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2022 - 01/2021
2NexusIBA
12/2021 - 02/2021
2Pharmaceutical PreparationsIBA
10/2021 - 12/2019
2Trefoil FactorsIBA
01/2020 - 04/2019
2CateninsIBA
05/2016 - 02/2016
2NicotineFDA Link
03/2011 - 02/2011
1Circulating Tumor DNAIBA
01/2022
1Tumor Biomarkers (Tumor Markers)IBA
01/2022
1serum P-component (CIt)IBA
12/2021
1Oncogene Proteins (Oncogene Protein)IBA
11/2021
1Ubiquitin-Specific ProteasesIBA
11/2021
1abexinostatIBA
10/2021
1MethyltransferasesIBA
10/2021
1DNA (Deoxyribonucleic Acid)IBA
10/2021
1Cyclin D1IBA
10/2021
1palbociclibIBA
10/2021
1curcumolIBA
01/2021
1Circular RNAIBA
01/2021
1CarcinogensIBA
01/2020
1Claudin-1IBA
01/2020
1ClaudinsIBA
01/2020
1CollagenIBA
01/2020
1Fibronectins (Fibronectin)IBA
01/2020
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
06/2019
1epidermal growth factor receptor VIIIIBA
06/2019
1Drug CombinationsIBA
06/2019
1N-acetyltalosaminuronic acid (NAT)IBA
04/2019
1IntegrinsIBA
08/2018
1Mucin-4IBA
08/2018
1ErbB Receptors (EGF Receptor)IBA
03/2017
1Calcibiotic Root Canal SealerIBA
05/2016
1Glycoproteins (Glycoprotein)IBA
04/2015
1Indicators and Reagents (Reagents)IBA
04/2015
1tyrosine receptor (receptor, tyrosine)IBA
01/2015
1Phosphotransferases (Kinase)IBA
01/2015
1Untranslated RNA (Noncoding RNA)IBA
01/2014
1Formaldehyde (Formol)FDA Link
01/2014
1HhAntag691IBA
01/2013
1Cadherins (E-Cadherin)IBA
10/2012
1Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA
10/2012
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
04/2011
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2011
1NF-kappa B (NF-kB)IBA
03/2011
1Interleukin-6 (Interleukin 6)IBA
03/2011
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
03/2011
1Culture MediaIBA
03/2011
1Serine (L-Serine)FDA Link
11/2010
1Carrier Proteins (Binding Protein)IBA
11/2010
1Protein Phosphatase 2 (Protein Phosphatase 2A)IBA
11/2010
1Threonine (L-Threonine)FDA Link
11/2010
1Activated-Leukocyte Cell Adhesion Molecule (Neurolin)IBA
05/2009

Therapy/Procedure

19Therapeutics
11/2022 - 11/2010
3Radiotherapy
12/2021 - 04/2018
2Immunotherapy
01/2022 - 12/2020
2Adjuvant Chemotherapy
12/2019 - 04/2018
1Precision Medicine
01/2022